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Biotechnology/Medical
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In Vitro Bioflavonoid Production
A technology to produce higher yields of these compounds than can be obtained from natural fruits.

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- Nutritional supplements
- Bioavailability markers
- Compound identification
- Food coloring
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Microdischarge Devices
Simply manufactured and low-cost technologies for robust, small, efficient, and versatile light-emitting devices.

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- Biomedicine
- Displays
- Specialty and general lighting
- Polymer curing
- Stereolithography
- Microetching
- Sensors
- Electronics
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Computer Software
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Perilog
Perilog is a contextual search method that provides a simple-to-use means of finding and ranking text documents according to their relevance to particular words or phrases.
+ Read the success story
+ Also read about this technology on our blog.
+ Read about how this technology is keeping our skies safe on our blog.

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Perilog can enhance many search-related applications, including:
- Large knowledge management and document retrieval systems, for legal research, market research, intellectual property asset management, claims management, etc.
- Life sciences and medical research
- Intelligence analyses
- Commercial search engines
- Contextual online advertising solutions
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Netmark
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- Enterprise knowledge management applications
- Document and content management systems
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Project Management Tool (PMT)
The PMT software is an advanced application that helps acquire and make the best use of consistent, timely, relevant business informationleading to better project and program decisions and plans.
+ Read the success story
+ Also read about this technology on our blog.

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- Enterprise knowledge management applications
- Document and content management systems
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PrimeSupplier Software
Using programmatic and enterprise demand data as well as industry financial benchmarks, this advanced software application forecasts economic influences on product and supplier viability throughout a product life cycle.
+ Also read about this technology on our blog.

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- Proactively manage suppliers’ economic stability
- Improve order fulfillment and on-time delivery
- Identify optimum timing for placing new procurement orders
- Minimize procurement overhead, obsolete inventory, and re-engineering to eliminate obsolete parts
- Take advantage of an excellent complement to Integrated Manufacturing Network/Supplier City and procurement simulation
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Data Processing
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Recursive Hierarchical Segmentation Software
Pre-processing software that significantly improves the extraction of patterns from complex data sets.

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- Aircraft or satellite remote sensing
- Medical imaging
- X-ray image analysis
- Image data mining
- Knowledge discovery and feature searches in large image database
- Image data fusion
- Facial recognition
- Thermal image analysis
- Nondestructive testing and evaluation
- Sonar and radar data analysis
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Electronics
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A High-Temperature Enabled Communication Circuit for DC Power Lines
A sensor and actuator networking innovation applicable to smart vehicle or component control. This innovation requires no additional connectivity beyond the wiring providing power.

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- Jet Engines
- Oil Field Services
- Power Turbines
- Biomedical Devices
- Nuclear Power Plants
- Factory Automation
- Solar Power Collectors
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Storing and Retrieving Data with High-Density Ferroelectric Memory
A device for storing and retrieving electronic data stores digital information as a multi-level digital or as an analog signal on a ferroelectric transistor that can be retrieved and converted back to the original digital data.
+ Also read about this technology on our blog.

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- High-speed computer RAM and hard drives
- Analog sensor data storage
- Radio Frequency Identification (RFID) systems
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Battery Management System
A novel circuit that provides simple, reliable, and safe battery management for high-voltage battery systems.
+ Also read about this technology on our blog

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- Electric vehicles (EVs), plug-in hybrid electric vehicles (PHEVs), and hybrid electric vehicles (HEVs)
- Telecommunications backup systems
- Space mission critical battery backup systems
- Uninterruptible power systems
- Electric utility storage for renewable energy
- High-voltage critical battery systems
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X-ray Diffraction Wafer Mapping Method
A powerful, non-destructive measurement tool
NASA’s Langley Research Center invites companies to license an innovative X-ray diffraction (XRD) method for determining twin defects in single crystals, poly-crystals, and crystalline structures at whole-wafer scale. This method will identify primary twin defects in wafers, benefiting wafer-level mass production of (111) plane-oriented cubic semiconductors such as silicon (Si), germanium (Ge), or SiGe on trigonal crystal substrates and enabling the fabrication of twin-free, rhombohedral single-crystalline SiGe layer regions.
+ Also read about this technology on our blog.

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- Semiconductor wafer processing
- Quality monitoring
- Quality control
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Reconfigurable SEU/SET Tolerance for FPGAs
This technology enables selective reconfiguration of field programmable gate arrays (FPGAs) and similar devices between redundant and non-redundant operation, to meet application needs for the right mix of reliability and high capacity. This innovation allows the flexibility of firmware redundancy while maintaining the efficiency and simplicity of hardware based redundancy.
+ Also read about this technology on our blog.

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This technology will be beneficial primarily in the high-radiation environments found in the aerospace industry. Key FPGA types include:
- Radiation-tolerant SRAM-based FPGAs
- Radiation-tolerant flash-based FPGAs
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Integral Battery Power Limiting Circuit for Intrinsically Safe Applications
Designed to limit the power output from a battery without compromising battery lifetime in situations where there is little headroom for dropping voltage or wasting current.
+ Also read about this technology on our blog.
+ Read about how this technology could help oil industry problems on our blog.

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- Transportation of natural gas or other potentially hazardous materials
- Offshore rigs and pipelines
- Mining applications, such as drilling and tunneling
- Gasoline pumps and hybrid vehicles
- Agriculture uses, such as grain elevators
- Medical monitoring equipment
- Field-based applications for military or other hazardous environments
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Microdischarge Devices
Simply manufactured and low-cost technologies for robust, small, efficient, and versatile light-emitting devices.

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- Biomedicine
- Displays
- Specialty and general lighting
- Polymer curing
- Stereolithography
- Microetching
- Sensors
- Electronics
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Production of Single-Walled Carbon Nanotubes
A major step forward in reducing the cost of manufacturing SWCNTs.

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- Medical
- Microelectronics
- Materials
- Molecular containment
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Rhombohedral Super Hetero Epitaxy of Silicon-Germanium (SiGe)
This is a fabrication method for the first rhombohedrally grown SiGe semiconductor alloy structure that will enable the development of ultra-fast chipsets exhibiting charge mobility of more than 3,000 cm2/Vswell beyond the state of the art for semiconductor chips.
+ Also read about this technology on our blog.

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- High electron mobility transistors and hetero-bipolar transistors used for high-speed computing and wireless communications
- Photovoltaic solar cells
- Thermoelectric systems
- Radiation detectors
- Optoelectronic devices with quantum wells
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Improvement of Crystalline Quality during Melt Growth of Semiconductors by Mechanically Induced Nucleation
A process to improve the crystal quality of semiconductor wafers, particularly II-VI wafers. Improved crystalline quality is achieved by reducing the rapid homogeneous nucleation of crystals that typically occurs when traditional solidification methods are used, allowing greater control and significantly increasing the yield of single crystal wafers that can be sliced from the boule.

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- X-ray detectors
- Gamma ray detectors
- Medical imaging
- Security imaging
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Micro-Coil Spring Interconnection for Ceramic Grid Array Packaged Integrated Circuits
A novel interconnection structure that replaces solder balls and solder columns for ceramic Ball Grid Array (BGA) packages. Provides flexibility in three dimensions between the ceramic package and the printed circuit board, preventing breaks due to thermal stress and increasing lifespan in harsh environments.

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- Automotive electronics
- Oilfield electronics
- Electronics for use in wet or humid environments
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Self-Regulating Control of Parasitic Electric Loads in Fuel Cell Power Systems
This technology is a method of power control for fuel cells that delivers increased power to internal or external parasitic devices, such as coolant pumping, sustaining heaters, or water separation. The method employs a self-regulating control function that eliminates the need for overly complex control strategies or external power controllers. The result is reduced fuel cell system complexity and greater reliability.

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- Cars and vehicles that run on fuel cells
- Uninterruptible power supplies
- Any power system when reliability and efficiency are primary concerns
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Environmental
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Solar-Powered Refrigeration System
This solar-powered refrigeration system eliminates reliance on an electric grid, requires no batteries, and stores thermal energy for efficient use when sunlight is absent.
+ Read about how this technology was licensed for off-grid refrigeration of vaccines on our blog.

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- Refrigerators
- Freezers
- Ice-makers
- Coolers
- Building air-cooling systems
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VaPRRS: A VOC/HAP Capture and Recovery System
Effectively captures volatile organic compounds and hazardous air pollutants and recovers them as pure liquids.

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- Painting and surface coating
- Printing
- Dry cleaners
- Chemical processing
- Indoor air quality control systems
- Manufacturing
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Human Health
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An Ultra-Efficient, Freeze-Resistant Hydration System
An innovative freeze-resistant hydration system that substantially improves on existing systems that cannot prevent water from freezing in the tubing, container, and mouthpiece in the harshest conditions on Earth.
+ Also read about this technology on our blog.
+ Does Water Freeze on Mount Everest? Find out on our blog.
+ NASA's high altitude hydration system wins R&D 100 award. Read about it on our blog.

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- Mountain climbers
- Downhill skiers
- Cross-country skiers
- Winter campers
- Snowmobilers
- Hunters
- Law enforcement and rescue personnel
- Defense environments, including SEAL, underwater, and deep sea use
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Manufacturing
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A Non-Contact, Remote, Micron Accuracy, Laser Fresnel Distance Ranging System
A state-of-the-art distance measurement system, with micron accuracy, at ranges of up to 20 meters from the target. Such measurement accuracy is accomplished by employing changes in laser Fresnel patterns, which are extraordinarily sensitive to changes in distance.
+ Also read about this technology on our blog.

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- Quality control operations (profiling to detect errors)
- Mold manufacturing (aerospace, automotive, shipbuilding, consumer products, and wind turbines)
- Steel work manufacturing
- Defense applications for careful machining of missile and other weapon system parts
- Milling machine calibration
- Computer hardware manufacturing (measuring thickness of hard drives to ensure balance)
- Dental/orthodontic appliance manufacturing
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Electron-Beam Freeform Fabrication (EBF3)
An innovative system for performing electron-beam freeform fabrication (EBF3) that offers significant advantages over traditional e-beam and laser-based systems.

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- Three-dimensional models for new designs
- Custom parts and small-batch production
- Chrome plating
- Replacement parts in remote or hostile locations
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Industrial Fluid Purification/Recovery
An improved method for purifying industrial process fluids such as parts washing detergent and metalworking coolant.

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- Aqueous parts washers
- Metalworking equipment
- Printing equipment
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ShuttleScan 3-D
The ShuttleSCAN 3-D surface scanning and profiling technology is an advanced system that can be used for a wide range of commercial applications from product quality control to autonomous navigation.

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- Inspection of aircraft and spacecraft fuselage surfaces, wings, etc.
- Autonomous navigation by mobile robots (e.g., Mars Rover)
- Inspection of pipelines (oil, natural gas, water) for corrosion-related defects
- Optical 3-D scanning of printed circuit boards for inspection and positioning
- Scanning reusable metal hardware sealing surfaces to detect flaws that would impact sealing ability
- Scanning industrial machined parts for dimensional accuracy
- Road surface profiling
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Universal Intelligent Control Platform
A flexible, modular, distributed control system that is easy to apply to industrial products.

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- Equipment
(automotive, agricultural, construction)
- Industrial automation
- Production lines
- Processing plants
- Motion control devices
- Building controls
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VaPRRS: A VOC/HAP Capture and Recovery System
Effectively captures volatile organic compounds and hazardous air pollutants and recovers them as pure liquids.

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- Painting and surface coating
- Printing
- Dry cleaners
- Chemical processing
- Indoor air quality control systems
- Manufacturing
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Mechanical
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Advanced Magnetostrictive Regulator and Valve
Effectively captures volatile organic compounds and hazardous air pollutants and recovers them as pure liquids.
+ Also read about this technology on our blog.

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- Pressure-fed rocket propulsion systems
- Aircraft engines
- Automotive fuel systems
- Manufacturing and Processing
- Petrochemicals
- Heated products (i.e., plastics)
- Pharmaceuticals
- Machinery
- Oil-flow control
- Air and gas compressors
- Steam turbines
- Power recovery
- Power-generating equipment
- Biomedical
- Device implants requiring pressure/flow control
- Drug metering systems
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- Pressure-fed propulsion systems
- Liquefied natural gas (LNG) and other fuel transportation
- Storage tanks for fuels, gases, and cryogenic fluids
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Composite Tank Technologies With Improved Structural Integrity
New designs and methods of fabrication for composite and composite-over-wrapped tank vessels help significantly improve their structural integrity against impact, abrasion, harsh environments, and fire.
+ Also read about this technology on our blog.

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- Pressure-fed propulsion systems
- Natural gas and other fuel transportation
- Self-contained breathing apparatus (SCBA) tanks for emergency responders
- Storage tanks for fuels, gases, and cryogenic fluids
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Self-Advancing Step-Tap Drill Bit
This novel, stepped drill bit features a cutting edge that concurrently enlarges a hole as it cuts threadsa feature not available in other stepped drill bits.
+ Also read about this technology on our blog.

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For construction and home shop use, especially:
- Drilling holes larger than 0.5 inch
- Drilling vertically oriented holes
- Repetitive drilling
- Overhead drilling
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Fluid Flow Metering and Mixing Technologies
A widely applicable suite of technologies with optimized capabilities for fluid metering, mixing, and conditioning. Each innovation within this suite is based on a core technology that has no moving parts, is simple to manufacture, and provides high reliability and efficiency. The base fluid plug technology can be modified with very few or no hardware changes to achieve the desired effect or combination of mixing, metering, and conditioning capabilities, depending on the application.
+ Also read about this technology on our blog.

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- Chemical processing facilities
- Manufacturing facilities
- Ground test facilities
- Industrial processing
- Petro-chemical processing
- Mechanical operations
- Mining
- Water analysis
- Liquid rocket engines
- Space propulsion
- Combustion nozzles
- Spray nozzles (e.g., shower heads)
- Variable orifice stream jets
- Venturi
- Density measurements
- Flow conditioners
- Compressor and pump inlets
- Near pipe bends, tees, elbows
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Vibration Isolation Systems
Eliminates between 90% and 99.94% of harmonic vibration in a lighter weight and lower cost system.

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- Rotating machinery
- Aerospace
- Automobiles
- Marine applications
- Power generating equipment
- Military applications
- Structural applications
- Large industrial sites
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Optics & Photonics
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Optical System and Method for Gas Detection and Monitoring
This gas sensor utilizes optical properties to monitor and detect leaks in pressurized systems, such as cryogenic tanks and distribution systems, and in vacuum conditions such as in space.
+ Also read about this technology on our blog.

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- Industrial manufacturing facilities
- Industrial storage facilities
- Facilities or processing involving or housing toxic, hazardous, or explosive gases
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Cryogenic and Non-Cryogenic Optical Liquid Level Instrument for Stratified Conditions
A simplified, cost-saving measurement device that uses optical transmission properties.
+ Also read about this technology on our blog.

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- Aerospace
- Rocket propulsion testing
- Engine fuel tanks
- Cryogenic tanks
- Automotive
- Liquid hydrogen fuel tanks
- Petroleum, gasoline, and liquid natural gas tanks
- Foods and Pharmaceuticals
- High-temperature, contamination-free storage and transportation
- Aviation
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Fiber Optic Shape Sensors
This shape-sensing technology offers high resolution (0.5-inch) and a 60-Hz refresh rate in a small, lightweight package that uses fiber Bragg grating (FBG) sensors and ultra-efficient, real-time algorithms.
+ Also read about this technology on our blog.

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- Aerospace
- Automotive
- Structures
- Wind Turbines
- Medical
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- Aerospace
- Automotive
- Structures
- Wind Turbines
- Medical
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Novel Grazing Incidence Neutron Optics
An optical component and low-cost manufacturing method, specifically optimized for neutron optics. It can be used as a lens and can be used to focus a broad beam source, broaden a narrow beam source, or focus an image of an object illuminated by, penetrated by, or giving off low energy neutrons.

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- Protein crystallography
- Nondestructive testing/inspection/evaluation (NDT/NDI/NDE), e.g., neutron tomography
- Medical imaging and treatment
- Detection and surveillance
- Neutron wave guides
- Extraterrestrial research
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Processing Equipment
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Froth Washer Attachment
A technology that produces a cleaner product using fewer flotation cells and/or processing runs, and results in a great reduction in costs.

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- Coal processing
- Paper recycling
- Soil remediation
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Sensors & Detectors
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Single Coil Absolute Position Sensor (SCAPS) with Inductive Gap Sensor (GapSyn) and Add-On Technologies
This technology suite includes a Single Coil Absolute Position Sensor (SCAPS) with Inductive Gap Sensor (GapSyn) and three associated technologies that can be incorporated into the primary technology to perform additional sensor functions and serve as a short-range antenna and close proximity transmitter and receiver.

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- Applications for these technologies span a broad range of industries and they can be combined to perform a variety of functions.
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Optical System and Method for Gas Detection and Monitoring
This gas sensor utilizes optical properties to monitor and detect leaks in pressurized systems, such as cryogenic tanks and distribution systems, and in vacuum conditions such as in space.
+ Also read about this technology on our blog.

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- Industrial manufacturing facilities
- Industrial storage facilities
- Facilities or processing involving or housing toxic, hazardous, or explosive gases
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Surface Acoustic Wave Sensor Arrays
A new technology for obtaining multiple, real-time measurements under extreme environmental conditions is being developed under Phase 1 and 2 funding contracts from NASA's Kennedy Space Center’s Small Business Technology Transfer (STTR) program. Opportunities for early deployment licensing and Phase 3 STTR contracts are now being accepted.

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- Cryogenic fluid level monitoring
- Spacecraft surfaces that experience extreme temperatures
- Turbine blade real-time stress and strain detection
- Vehicle acceleration force monitoring
- Rotational and directional sensing
- Critical pressure loss detection
- Toxic safety monitoring
- Process safety monitoring (such as gas and oil industrial refining)
- Variable measurement within sealed containers or in difficult-to-reach locations
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- Aerospace
- Automotive
- Structures
- Wind Turbines
- Medical
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Fiber Optic Shape Sensors
This shape-sensing technology offers high resolution (0.5-inch) and a 60-Hz refresh rate in a small, lightweight package that uses fiber Bragg grating (FBG) sensors and ultra-efficient, real-time algorithms.
+ Also read about this technology on our blog.

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- Aerospace
- Automotive
- Structures
- Wind Turbines
- Medical
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ShuttleScan 3-D
The ShuttleSCAN 3-D surface scanning and profiling technology is an advanced system that can be used for a wide range of commercial applications from product quality control to autonomous navigation.
+ Also read about this technology on our blog.

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|
- Inspection of aircraft and spacecraft fuselage surfaces, wings, etc.
- Autonomous navigation by mobile robots (e.g., Mars Rover)
- Inspection of pipelines (oil, natural gas, water) for corrosion-related defects
- Optical 3-D scanning of printed circuit boards for inspection and positioning
- Scanning reusable metal hardware sealing surfaces to detect flaws that would impact sealing ability
- Scanning industrial machined parts for dimensional accuracy
- Road surface profiling
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Monitor of RF-Induced Currents
This patented, wearable device provides a superior means for monitoring radio frequency (RF)-induced currents in the human body, making it useful for operators of RF equipment in plastics manufacturing, personnel who work with antennas or transmitters, and others exposed to RF radiation.

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- Plastics manufacturing
- Broadcasting
- Military
- Antenna design
- Cancer treatment
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Cryogenic and Non-Cryogenic Optical Liquid Level Instrument for Stratified Conditions
A simplified, cost-saving measurement device that uses optical transmission properties.
+ Also read about this technology on our blog.

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- Aerospace
- Rocket propulsion testing
- Engine fuel tanks
- Cryogenic tanks
- Automotive
- Liquid hydrogen fuel tanks
- Petroleum, gasoline, and liquid natural gas tanks
- Foods and Pharmaceuticals
- High-temperature, contamination-free storage and transportation
- Aviation
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Hermetic Seal Leak Detection
A device for nondestructive testing (NDT) of hermetic seals of containers or instrumentation. Capable of detecting both large and small leaks and characterizing relative leak rates. Does not require the seal to be pressurized or the use of expensive instrumentation such as a mass spectrometer to analyze leaks.

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- Electronic equipment such as semiconductors, thermostats, optical devices
- Packaging for consumer goods such as food, pharmaceuticals, chemicals
- Equipment used in specialized situations such as in harsh environments for military or field lab use, controlled environments like clean rooms, or highly explosive areas
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Optical System and Method for Gas Detection and Monitoring
Optical interferometer for detecting the presence of gas by measuring interference shift patterns across a small gap.
+ Also read about this technology on our blog.

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- Vacuum jacketed pipes
- Cryogenic storage
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Telecommunications & Internet
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Ad Hoc Selection for Voice Over Internet Streams
This new method and apparatus distributes audio streams, in the form of encrypted data packets, to the personal computers of authorized listeners in near real time.
+ Also read about this technology on our blog.

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Audio Multicasting and Monitoring
- Air-traffic training applications
- EMS communications
- Telemedicine, stock exchange, and other information and data sharing
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Cellular Reflectarray Antenna
This new concept design for terrestrial satellite dishes and communications systems has been developed and tested for use with next-generation Ka-band satellites, although it can be used with all bands of satellite communication. The design’s flat, planar configuration all but eliminates the wind-loading problems associated with larger parabolic reflectors for dish systems. The technology also offers unique features that provide ease of installation and improved signal reception while deterring piracy and theft of subscription satellite services.
+ Also read about this technology on our blog.

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- Broadband satellite communications
- Emergency communications (e.g., disaster response and recovery)
- Military applications
- Back-up communication for large events (e.g., Olympics, concerts, conventions)
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